Which root would indicate a relationship to bones, specifically indicating mineral content?

The root that indicates a relationship to bones and specifically refers to mineral content is "calc/o." This root comes from the Latin word "calx," meaning lime or calcium, which is a key mineral found in bones. Calcium plays a crucial role in bone density and strength, making "calc/o" an appropriate choice when discussing bone-related terminology, especially in contexts involving mineral content.

In contrast, "burs/o" refers to the bursa, a small fluid-filled sac that helps reduce friction in joints. "Blephar/o" pertains to the eyelid, and "bucc/o" relates to the cheek. These roots do not have any connection to bones or their mineral content, underscoring why "calc/o" is the best choice for the given question.